2025 -  WEEK 6 - What's New in RWE Research

 

 

  1. The Healthcare Integrated Research Database (HIRD) as a Real-World Data Source for Pharmacoepidemiologic Research. Barron JJ, Willey VJ, Doherty BT, Tunceli O, Waltz CR, Grabner M, Beachler DC, Lanes S, Cziraky MJ. Pharmacoepidemiol Drug Saf. 2025 Feb;34(2):e70110. doi: 10.1002/pds.70110. PMID: 39909722

 

  1. Real-world data of dacomitinib as first-line treatment for patients with EGFR-mutant non-small-cell lung cancer. Shin JE, Jung HA, Park S, Sun JM, Lee SH, Ahn JS, Ahn MJ, Shim BY.Sci Rep. 2025 Feb 7;15(1):4593. doi: 10.1038/s41598-024-81704-4.PMID: 39920167

 

  1. Project Victoria: A pragmatic data model to automate RWE generation from the national French claims database. Ouazzani K, Ansolabehere X, Journeau F, Vidal A, Jaubourg N, Doublet M, Thollot R, Fabre A, Glatt N. Health Informatics J. 2025 Jan-Mar;31(1):14604582251318250. doi: 10.1177/14604582251318250. PMID: 39913942

 

  1. Sex Disparities of Health-related Quality of Life in Moderate to Severe Psoriasis: A Real-world Analysis from the Swiss Psoriasis Registry (SDNTT). Lichtenberger R, Maul LV, Birkenmaier I, Oyanguren I, Ak M, Heidemeyer K, Schlapbach C, Yawalkar N, Egeberg A, Thomsen SF, Thyssen JP, Sorbe C, Boehncke WH, Conrad C, Cozzio A, Kokolakis G, Micheroli R, Wu JJ, Kündig T, Navarini A, Maul JT.Acta Derm Venereol. 2025 Feb 6;105:adv42296. doi: 10.2340/actadv.v105.42296.PMID: 39916484

 

  1. An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets. Graefe ASL, Hübner MR, Rehburg F, Sander S, Klopfenstein SAI, Alkarkoukly S, Grönke A, Weyersberg A, Danis D, Zschüntzsch J, Nyoungui EF, Wiegand S, Kühnen P, Robinson PN, Beyan O, Thun S.Sci Data. 2025 Feb 8;12(1):234. doi: 10.1038/s41597-025-04558-z.PMID: 39922817

 

  1. High risk for life-threatening adverse events of fluoroquinolones in young adults: a large German population-based cohort study. Wicherski J, Peltner J, Becker C, Schüssel K, Brückner G, Schlotmann A, Schröder H, Kern WV, Haenisch B.BMC Med. 2025 Feb 7;23(1):76. doi: 10.1186/s12916-025-03919-0.PMID: 39920723.

 

  1. Adverse events in the nervous system associated with blinatumomab: a real-world study. Gao W, Yu J, Sun Y, Song Z, Liu X, Han X, Li L, Qiu L, Zhou S, Qian Z, Wang X, Zhang H.BMC Med. 2025 Feb 6;23(1):72. doi: 10.1186/s12916-025-03913-6.PMID: 39915776 

 

  1. Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma. Bruno DS, Khanal M, Li X, Escalon MP, Winfree K, Hess LM. 2025 Dec;30(1):2457809. doi: 10.1080/16078454.2025.2457809. Epub 2025 Feb 5.PMID: 39910811.

 

  1. Chitosan-covered tamponade for the treatment of postpartum hemorrhage: a registry-based cohort study assessing outcomes and risk factors for treatment failure. Leichtle C, Aigner A, Biele C, Hermann P, Dangli T, Waldner C, Braun T, Henrich W, Dückelmann AM.BMC Pregnancy Childbirth. 2025 Feb 5;25(1):120. doi: 10.1186/s12884-025-07236-5.PMID: 39910452 

 

  1. Prevalence, influencing factors, and prediction model construction of anemia in ankylosing spondylitis based on real-world data: An exploratory study. Gong Y, Yang K, Geng Z, Liu H. PLoS One. 2025 Feb 5;20(2):e0318332. doi: 10.1371/journal.pone.0318332. eCollection 2025.PMID: 39908327 

 

  1. Outcomes of Pembrolizumab plus chemotherapy for patients with metastatic non-squamous NSCLC: Real-world evidence. Surovtsova I, Herth FJF, Kokh DB, Morakis P. 2025 Dec 31;31(1):2457856. doi: 10.1080/25310429.2025.2457856. Epub 2025 Feb 5.PMID: 39907049 

 

  1. Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review. Maurice P, McCallion J, Fitzgibbon M, Barthelmes JN, Karmous W, Hardy EJ, Mitchell SA, Mitchell CR, Lee J, Noel W, Borsi A, Jouannic JM.BMC Pregnancy Childbirth. 2025 Feb 4;25(1):114. doi: 10.1186/s12884-025-07208-9.PMID: 39905388 

 

  1. Has a fast treatment transition from surgical to endovascular operations improved the survival of aneurysmal subarachnoid hemorrhage? Asikainen A, Rautalin I, Raj R, Korja M, Niemelä M. Acta Neurochir (Wien). 2025 Feb 4;167(1):34. doi: 10.1007/s00701-025-06447-1.PMID: 39904810 

 

  1. Cost-effectiveness analysis of fosnetupitant in patients receiving cisplatin in Japan: analysis based on real-world data. Inano H, Morimoto Y, Kitagawa K, Shibuya A, Nakagomi K, Ota T, Anzo Y, Miyauchi R, Shono A, Watanabe K, Otori K.Support Care Cancer. 2025 Feb 4;33(2):149. doi: 10.1007/s00520-025-09210-5.PMID: 39904775

 

  1. Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y global registry. Cortellini A, Brunetti L, Di Fazio GR, et al. J Immunother Cancer. 2025 Feb 4;13(2):e010674. doi: 10.1136/jitc-2024-010674.PMID: 39904562 

 

  1. The Data Artifacts Glossary: a community-based repository for bias on health datasets. Gameiro RR, Woite NL, Sauer CM, Hao S, Fernandes CO, Premo AE, Teixeira AR, Resli I, Wong AI, Celi LA.J Biomed Sci. 2025 Feb 4;32(1):14. doi: 10.1186/s12929-024-01106-6.PMID: 39901158 

 

  1. Collecting Real-World Data via an In-Home Smart Medication Dispenser: Longitudinal Observational Study of Survey Panel Persistency, Response Rates, and Psychometric Properties. Ogorek B, Rhoads T, Smith E.JMIR Hum Factors. 2025 Feb 3;12:e60438. doi: 10.2196/60438.PMID: 39899755 

 

  1. Effectiveness of an Impella Versus Intra-Aortic Balloon Pump in Patients Who Received Extracorporeal Membrane Oxygenation. Nishimoto Y, Ohbe H, Nakata J, Takiguchi T, Nakajima M, Sasabuchi Y, Isogai T, Matsui H, Sato Y, Watanabe T, Yamada T, Fukunami M, Yasunaga H.J Am Heart Assoc. 2025 Feb 4;14(3):e037652. doi: 10.1161/JAHA.124.037652. Epub 2025 Feb 3.PMID: 39895529 

 

  1. Chinese herbal medicines and its active ingredient wogonin can improve immune inflammation in psoriatic arthritis. Zhang XH, Liu J, Ding X, Chen XL.Int Immunopharmacol. 2025 Feb 6;147:113984. doi: 10.1016/j.intimp.2024.113984. Epub 2025 Jan 2.PMID: 39752753

 

  1. Quality of life improvement after radiotherapy for bone metastases assessed using real-world data: a secondary analysis of a Nationwide Multicenter Cohort Study. Utsumi N, Saito T, Shikama N, Takahashi T, Harada H, Nakamura N, Ueno S, Notsu A, Shirato H, Yamada K, Uezono H, Koide Y, Kubota H, Yamazaki T, Ito K, Heianna J, Okada Y, Tonari A, Katoh N, Wada H, Ejima Y, Yoshida K, Kosugi T, Takahashi S, Komiyama T, Uchida N, Miwa M, Watanabe M, Nagakura H, Ikeda H, Asakawa I, Shigematsu N. Jpn J Clin Oncol. 2025 Feb 4;55(2):140-147. doi: 10.1093/jjco/hyae150.PMID: 39479804

 

  1. Lower Mortality Risk Associated With Remdesivir + Dexamethasone Versus Dexamethasone Alone for the Treatment of Patients Hospitalized for COVID-19. Mozaffari E, Chandak A, Gottlieb RL, Chima-Melton C, Berry M, Oppelt T, Okulicz JF, Amin AN, Welte T, Sax PE, Kalil AC.Clin Infect Dis. 2025 Feb 5;80(1):63-71. doi: 10.1093/cid/ciae477.PMID: 39302162

 

  1. Phosphodiesterase 5 and its inhibitors with ischaemic heart disease: a Mendelian randomization analysis and a real-world study. Xiao J, Zhang N, Gao Z, Wei Y, Wei H, Qiu Z, Sundquist K, Sundquist J, Ji J, Huang W.Eur Heart J Cardiovasc Pharmacother. 2025 Feb 8;11(1):75-83. doi: 10.1093/ehjcvp/pvae081.PMID: 39424597.

 

REVIEWS

 

  1. Machine learning research methods to predict postoperative pain and opioid use: a narrative review. Langford DJ, Reichel JF, Zhong H, Basseri BH, Koch MP, Kolady R, Liu J, Sideris A, Dworkin RH, Poeran J, Wu CL.Reg Anesth Pain Med. 2025 Feb 5;50(2):102-109. doi: 10.1136/rapm-2024-105603.PMID: 39909542 Review.

 

  1. Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis. Rodriguez-Iglesias M, Calvo-Henríquez C, Martin-Jimenez D, García-Lliberós A, Maza-Solano J, Moreno-Luna R, Izquierdo-Domínguez A, Martínez-Capoccioni G, Alobid I.Curr Allergy Asthma Rep. 2025 Feb 5;25(1):13. doi: 10.1007/s11882-025-01192-y.PMID: 39907855  Review.

 

  1. Mechanical circulatory support for complex, high-risk percutaneous coronary intervention. Ferro EG, Kim JM, Lalani C, Abbott DJ, Yeh RW. 2025 Feb 3;21(3):e149-e160. doi: 10.4244/EIJ-D-24-00386.PMID: 39901631  Review.

 

  1. Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review. Maurice P, McCallion J, Fitzgibbon M, Barthelmes JN, Karmous W, Hardy EJ, Mitchell SA, Mitchell CR, Lee J, Noel W, Borsi A, Jouannic JM. BMC Pregnancy Childbirth. 2025 Feb 4;25(1):114. doi: 10.1186/s12884-025-07208-9.PMID: 39905388